Value of apparent diffusion coefficient factor in correlation with the molecular subtypes, tumor grade, and expression of Ki-67 in breast cancer

Abstract Background Breast cancer is known to be the most common in women; last decade, contrast-enhanced magnetic resonance imaging has become an important tool diagnosis of breast. Numerous studies have analyzed associations between and histopathological features as well proliferation potential breast cancer. The purpose this study was evaluate relationship apparent diffusion coefficient (ADC) expression Ki-67 tumor molecular subtype Results No significant difference mean ADC value tumors grade I, II, III found. However, there a type A B ( P = 0.000), HER2 overexpression 0.018), TN respectively. no B, TN. Also, found III. Yet 0.014), overexpression, Conclusions There inverse correlation values expression. DWI could good discriminator from other subtypes, yet it did not show with grade.